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Generally Investor friendly
STRs are not banned and likely allowed citywide; the city requires only a simple Residential Occupancy Permit (ROP) with an inspection and a low $15 fee, plus standard housing and state tax compliance—no specific STR caps or city lodging taxes. The main caveat is that zoning (Chapter 26) must confirm STRs are permitted in the district; if allowed, the process is straightforward and investor-friendly.
Local STR Agent
STR specialist · Potosi, MO
Potosi is a small city in Washington County in the eastern Ozarks of southeastern Missouri, serving as the county seat with a population of roughly 2,600 residents. The town has a quiet, rural character rooted in its early-19th-century history as one of the most productive lead-mining districts in the United States, a heritage that still defines its identity today. Surrounded by forested hills, springs, and the rolling landscape of the St. Francois Mountains, Potosi is best known as a base for exploring the Mark Twain National Forest and the cluster of state parks and historic mining sites that lie within an hour's drive. It sits approximately 75 miles southwest of St. Louis, making it a manageable drive for visitors coming from the metropolitan area or from the I-44 corridor.
One of the closest outdoor escapes is Washington State Park, located just a few miles south of town. The park surrounds a clear lake and offers a sandy swimming beach, paved hiking and biking trails, picnic areas, and a campground, making it a popular spot for both day visits and overnight stays. Its proximity to Potosi gives visitors a quick way to enjoy the Ozark outdoors without long drives.
A short drive east brings travelers to the historic mining town of Bonne Terre and the Bonne Terre Mine, one of the region's most unusual attractions. This vast former lead mine, once one of the largest in the world, has been converted into a year-round attraction featuring walking tours, boat tours across the flooded lower levels, and scuba diving among submerged mining equipment and rock walls. The experience draws visitors interested in geology, history, and adventure alike.
South of Potosi, the broader region offers additional outdoor destinations, including Elephant Rocks State Park, where massive granite boulders form a natural climbing and exploration area, and stretches of the Mark Twain National Forest that offer hiking, hunting, and scenic drives through the Ozark highlands. Together, these natural areas give short-term rental guests a wide range of low-key outdoor activities within a short drive of town.
Potosi's combination of rural Ozark charm, deep mining-era history, and access to state parks, the Mark Twain National Forest, and unique attractions like Bonne Terre Mine makes it a compelling base for short-term rentals. Guests can enjoy a small-town atmosphere while staying within easy reach of hiking, swimming, scuba diving, and the natural beauty of southeastern Missouri.